Symbol
Name
ID

Tlr4
toll-like receptor 4
MGI:96824

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes

Retinal arteritis

Conjunctivitis

Double outlet right ventricle with subpulmonary ventricular septal defect without pulmonary stenosis

Pericarditis

Abdominal aortic aneurysm

Aortic dissection

Premature coronary artery atherosclerosis

Vasculitis

Hypertension

Raynaud phenomenon

Cerebral ischemia

Arrhythmia

Sudden cardiac death

Myocardial infarction

Lymphadenopathy

Mediastinal lymphadenopathy

Splenomegaly

Iris hypoperfusion

Retinal vein occlusion

Erythema

Facial erythema

Disease(s) Associated with TLR4

atopic dermatitis

Behcet's disease

coronary artery disease

exfoliation syndrome

familial mediterranean fever

temporal arteritis

Mouse Phenotypes		abnormal artery morphology	atherosclerotic lesions	decreased angiogenesis	rectal hemorrhage	decreased response of heart to induced stress	abnormal vascular wound healing
Availability	Mouse Genotype	abnormal artery morphology	atherosclerotic lesions	decreased angiogenesis	rectal hemorrhage	decreased response of heart to induced stress	abnormal vascular wound healing
	Tlr4^Lps-d/Tlr4^Lps-d
	Tlr4^lps-del/Tlr4^lps-del

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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